473. RF Interstitial hyperthermia, fundamental experiments for clinical applications

OLD CS 473: Fundamental Algorithms

Clinical applications of magnetic nanoparticles for hyperthermia.

Magnetic fluids are increasingly used for clinical applications such as drug delivery, magnetic resonance imaging and magnetic fluid hyperthermia. The latter technique that has been developed as a cancer treatment for several decades comprises the injection of magnetic nanoparticles into tumors and their subsequent heating in an alternating magnetic field. Depending on the applied temperature a...

New magnetic implant material for interstitial hyperthermia

Magnetic properties and heat generation characteristics of a bio-compatible ceramic Mg1þxFe222xTixO4 system have been investigated as an implant material for the magnetic induction hyperthermia. Curie temperature ðTcÞ of the ceramic decreases with increasing x; and become Tc , 350 K at x 1⁄4 0:35 and ,315 K at x 1⁄4 0:38; which is suitable Curie temperature for implant material. The temperature...

Local Hyperthermia with Interstitial Techniques1

The heating of deep visceral tumors with implanted electrodes and with self-regulating ferromagnetic thermoseeds was inves tigated. Clinical trials on six patients heated with implanted electrodes indicate that good local tumor control can be obtained by application of hyperthermia during a normal course of radio therapy. The heating method was found practical, and neither toxicity nor severe p...

Intracellular Hyperthermia Using Magnetic Nanoparticles: A Novel Method for Hyperthermia Clinical Applications

Magnetic nanoparticle-mediated intracellular hyperthermia has been a largely experimental modality of hyperthermia, but this treatment modality has the potential to achieve tumor targeted heating without any side effects. The technique consists of targeting magnetic nanoparticles to tumor tissue and then applying an external alternating magnetic field to induce heat generation by the magnetic n...